Cell Culture Services
Cell Culture Services
Your therapy is as unique as the challenges you will be facing. Our Cell Culture Services Team understands that and is tasked with helping you moving your project as quickly and successfully as possible to the next stage. Over 30 years of servicing experience in the Pharma and Biotech space have taught us that “placing the customer at the center“ means involving all stakeholders and departments in the project, partnering to find out-of-the-box solutions, holding the mirror high and pointing at the blind spots, and most of all planning for success by holding ourselves and our customers accountable for measurable progress.
Our Cell Culture services have been specifically designed to solve modern challenges in the development of Small Molecules, Large Molecules, Cell Therapies, Gene Therapies, ATMPs and Vaccines, including:
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Early development of assays to address safety concerns
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Streamlining development efforts from pre-clinic to clinic
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Maintaining flexibility and expansion of working capacity for critical R&D stages
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Dependability of supplier relationship for in-time and on-budget project completion
For more information of how we partner with our customers, visit the page
Immunogenicity and Immunotoxicity Services
Immunogenicity and immunotoxicity constitute important challenges during the development of new Biotherapeutics, Vaccines, Cell and Gene Therapies, and their evaluation is pivotal to guarantee the safety and efficacy of new therapeutic solutions.
Our Cell Culture Services team has developed a range of in vitro assays including:
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T-Cell activation and proliferation
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Innate immune cells activation and proliferation
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DC:T-cell stimulation assays
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Cytokine Storm assay
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Purification of proteins from plasma or serum
BIOMEX‘s Immunogenicity and Immunotoxicity Services are designed to provide you with comprehensive information on the risk profile of your therapeutic candidate and enable you to further refine, humanize or engineer your biotherpeutic and evaluate its potency and efficacy. In order to do so, our team will perform a preliminary in silico analysis, followed by in vitro assays to identify immunogenic epitopes, study the interaction of immune cells and identify suitable candidates. Once the first insights have been identified, a more detailed testing stragy will be discussed according to your project. Additional evaluation of cell proliferation, viability, signaling, activation, gene expression, cell-cell interaction and differentiation can be requested in addition and performed either in-house or through collaborating partners.
Additional testing or modification of existing Catalog Products
BIOMEX has developed its standard catalog products in order to fit the most common applications in basic research and drug discovery. Not in all cases the available formats or characterization may fit your specific application, but more often than not we will be able to modify them or add additional testing as you may require.
Possible modifications include:
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Additional viral testing
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Additional FACS or ELISA testing
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Additional polymorfism analysis
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Pooled donors
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Pooled cells
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Pre-seeding of 3D matrixes or plates
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Different cell quantity per vial
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Different cryopreservation media
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Different passage number
Cell expansion and Biobanking
Our cell expansion and Biobanking services have been designed to support our customers as an external workbennch to expand their working capacity. Especially during periods of economic downturn or increase workload, developers want to maintain flexibility in their pipeline while developing enough capability in their R&D to focus on important or urgent projects.
Our Cell Culture Service team can support you with:
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Cell culture and expansion of primary cells and cell lines
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Generation of Master and Working Cell Banks
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Cell Characterization, QC and QA
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Delivery of expanded cells or performance of assays developed in-house or co-developed
Dedicated tissue sourcing and cell isolation
BIOMEX manages three plasma centers in Central Europe and Africa and has access to a wide network of partners in clinics and hospitals, allowing to souce a wide range of human cells and tissues from healthy and diseased donors.
Our Cell Culture Services team can support you with:
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Tissue Sourcing
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Dedicated cell isolations
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Characterisation of isolated cells
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Logistics of isolated tissues and cell
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Paraffin embedding and slice preparation and banking
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Storage and cryopreservation
For more information of how we partner with our customers, visit the page
To inquire about the feasibility of any modification of our catolog products, make sure to contact us!
Our Experts for Life Sciences
Unlock the potential of your research with our high-quality biospecimens and expert services. At BIOMEX, we believe that working with our customers is the best way to improve project success and reduce costs and development time.