ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicity), is a crucial aspect of drug development and the assessment of the safety and efficacy of new compounds. Understanding ADME-Tox properties of a drug candidate is essential for identifying potential issues early in the development process and determining appropriate dosing regimens. 

Our Pharmacodynamics (PD) services support the ADME-Tox and preclinical safety aspects of the drug discovery and development process. 

Our experienced team of scientists has extensive expertise in PD assay development, in vivo efficacy studies, and biomarker discovery. We work closely with our clients to design and conduct studies that provide a comprehensive understanding of the PD properties of their drug candidates. 

Our PD services include:

  • PD assay development

    We develop and validate assays to measure the biological activity of drug candidates in various disease models.

  • In vivo efficacy studies

    We conduct efficacy studies in various animal models to evaluate the therapeutic potential of drug candidates.

  • Biomarker discovery

    We use advanced technologies such as transcriptomics, proteomics, and metabolomics to identify biomarkers that can be used to monitor the efficacy and safety of drug candidates.

  • ADME-Tox / Preclinical Safety evaluation

    We provide our clients with a comprehensive understanding of the drug's pharmacokinetics, pharmacodynamics, and toxicological properties, allowing them to evaluate the safety profile of their drug candidates.

We understand the importance of timely and reliable data in the drug discovery and development process, that is why we are committed to providing our clients with the highest level of service and support. Our team of experts work closely with our clients to understand their specific needs and develop tailored solutions to support their drug discovery and development efforts. 

At BIOMEX, we are dedicated to providing the highest quality data and services to support our clients’ drug discovery and development efforts. To learn more about our PD services and how we can support your ADME-Tox / Preclinical Safety evaluation, please contact us today.

We look forward to working with you!

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