Syphilis Seroconversion Panel
Syphilis Seroconversion Panel –
Increase your diagnostic sensitivity.
Our syphilis seroconversion panel represents a significant advancement in syphilis diagnostics by providing a comprehensive view of the serological course of a Treponema pallidum infection. It is an important tool for improving the sensitivity of serological tests, which is very useful for the early diagnosis of syphilis.
This panel fills a critical gap in the field by providing well-characterized data on the progression from a healthy state through initial infection to the various stages of disease development and recovery.
Because the samples cover the entire course of infection, they demonstrate the full development of both non-treponemal and treponemal antibody responses. Such a comprehensive panel allows the evaluation of test performance across the entire spectrum of infection, from the first serological changes to the establishment of a robust immune response.
Key Features
- Comprehensive Serological History: Provides a complete profile of serological changes during the course of syphilis infection, allowing detailed analysis of antibody development and fluctuations.
- High-Resolution Sequential Serology: Captures the nuanced progression of infection from onset to resolution with closely spaced sampling intervals of 3-4 days over a 149-day period in this seroconversion panel.
- Detailed Donor Clinical Profile: Comprehensive documentation of symptomatology and clinical manifestations that provides context to the serological data.
- Documentation of Antibiotic Treatment: Provides accurate information on antibiotics administered, allowing correlation between therapeutic measures and serological responses.
- Regulatory Compliance: Manufactured in compliance with European Union standards and CE certified, ensuring adherence to strict quality and safety protocols
Need more information?
This information enables accurate assessment of test performance at different stages of infection and facilitates the optimisation of cut-off values and analytical sensitivity. The panel is a valuable tool for researchers and diagnostic manufacturers in the development and validation of more sensitive syphilis detection methods.
The panel contains the following key elements to improve diagnostic sensitivity:
- Donor profile with symptom and treatment information
- Comprehensive serological follow-up data
- Results from different diagnostic platforms for comparative analysis
- Detailed breakdown of specific antibody responses (TpN47, TpN17, TpN15, TmpA)
