{"id":17877,"date":"2024-10-18T15:48:33","date_gmt":"2024-10-18T13:48:33","guid":{"rendered":"https:\/\/biomex-stage.ultrabold.de\/?page_id=17877"},"modified":"2024-10-21T09:35:28","modified_gmt":"2024-10-21T07:35:28","slug":"%e7%94%9f%e7%89%a9%e6%89%93%e5%8d%b0%ef%bc%9a%e5%88%9b%e9%80%a0%e7%94%9f%e5%91%bd%e7%9a%84%e8%89%ba%e6%9c%af%e4%b8%8e%e7%a7%91%e5%ad%a6","status":"publish","type":"page","link":"https:\/\/biomex.de\/zh-hans\/%e7%94%9f%e7%89%a9%e6%89%93%e5%8d%b0%ef%bc%9a%e5%88%9b%e9%80%a0%e7%94%9f%e5%91%bd%e7%9a%84%e8%89%ba%e6%9c%af%e4%b8%8e%e7%a7%91%e5%ad%a6\/","title":{"rendered":"\u751f\u7269\u6253\u5370\uff1a\u521b\u9020\u751f\u547d\u7684\u827a\u672f\u4e0e\u79d1\u5b66"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"17877\" class=\"elementor elementor-17877 elementor-17791\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e641917 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"e641917\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e84988c\" data-id=\"e84988c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-33d1a27 elementor-widget elementor-widget-template\" data-id=\"33d1a27\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"template.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-template\">\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-section elementor-top-section elementor-element elementor-element-6a72c14 elementor-section-full_width elementor-section-stretched elementor-section-height-default elementor-section-height-default\" data-id=\"6a72c14\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a2c09a6\" data-id=\"a2c09a6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c3c0ac1 breadcrumb elementor-widget elementor-widget-shortcode\" data-id=\"c3c0ac1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"16139\" class=\"elementor elementor-16139 elementor-1114 elementor-1114\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-60cebac9 elementor-section-full_width elementor-section-height-min-height elementor-section-height-default elementor-section-items-middle\" data-id=\"60cebac9\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-36426147\" data-id=\"36426147\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-16722c7e elementor-align-left elementor-widget elementor-widget-breadcrumbs\" data-id=\"16722c7e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"breadcrumbs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"breadcrumbs\"><span><span><a href=\"https:\/\/biomex.de\/zh-hans\/\">Home<\/a><\/span><\/span><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9facf1e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9facf1e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0cc50c7\" data-id=\"0cc50c7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5540d18 elementor-widget elementor-widget-spacer\" data-id=\"5540d18\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1a82682 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1a82682\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-317b90e\" data-id=\"317b90e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e9ebb78 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"e9ebb78\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">\u751f\u7269\u6253\u5370\uff1a\u521b\u9020\u751f\u547d\u7684\u827a\u672f\u4e0e\u79d1\u5b66<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-811b24b elementor-widget elementor-widget-spacer\" data-id=\"811b24b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-f9716d2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f9716d2\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-f836db0\" data-id=\"f836db0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4809269 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"4809269\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u751f\u547d\u79d1\u5b66\u9ad8\u7ea7\u79d1\u5b66\u5bb6Djeda Belharazem\u535a\u58eb <a href=\"mailto:djeda.belharazem@biomex.de\">djeda.belharazem@biomex.de<\/a><\/p><p>\u9500\u552e\u4e0e\u9879\u76ee\u526f\u603b\u88c1Manish Kumar\u535a\u58eb <a href=\"mailto:manish.kumar@biomex.de\">manish.kumar@biomex.de<\/a><\/p><p>\u751f\u7269\u6253\u5370\u6280\u672f\u6b63\u5728\u5c06\u6253\u5370\u5fc3\u810f\u3001\u76ae\u80a4\u548c\u8f6f\u9aa8\u7b49\u529f\u80fd\u6027\u7ec4\u7ec7\u7684\u79d1\u5e7b\u68a6\u60f3\u53d8\u4e3a\u73b0\u5b9e\u3002\u751f\u7269\u6253\u5370\u6280\u672f\u5229\u7528\u5148\u8fdb\u76843D\u6253\u5370\u6280\u672f\uff0c\u5c06\u6d3b\u7ec6\u80de\u3001\u751f\u7269\u6750\u6599\u548c\u751f\u957f\u56e0\u5b50\u5206\u5c42\uff0c\u4ee5\u521b\u5efa\u4e0e\u5929\u7136\u7ec4\u7ec7\u9ad8\u5ea6\u76f8\u4f3c\u7684\u751f\u7269\u7ed3\u6784\u3002\u8fd9\u9879\u6280\u672f\u7684\u7cbe\u786e\u6027\u548c\u591a\u529f\u80fd\u6027\u4f7f\u79d1\u5b66\u5bb6\u80fd\u591f\u590d\u5236\u7ec4\u7ec7\u7684\u590d\u6742\u7ed3\u6784\uff0c\u4f7f\u6211\u4eec\u79bb\u5236\u9020\u6574\u4e2a\u5668\u5b98\u7684\u76ee\u6807\u66f4\u8fd1\u4e86\u4e00\u6b65\uff08Murphy &amp; Atala\uff0c2014\uff09\u3002<\/p><p><strong>\u751f\u7269\u6253\u5370\u7684\u5173\u952e\u6280\u672f\uff1a<\/strong><\/p><ol><li>\u55b7\u58a8\u751f\u7269\u6253\u5370\uff1a\u8fd9\u79cd\u65b9\u6cd5\u4ee5\u9ad8\u7cbe\u5ea6\u548c\u5feb\u901f\u8457\u79f0\uff0c\u7279\u522b\u9002\u7528\u4e8e\u751f\u4ea7\u76ae\u80a4\u548c\u8f6f\u9aa8\uff0c\u56e0\u4e3a\u7ec6\u80de\u5728\u5176\u4e2d\u7684\u7cbe\u786e\u653e\u7f6e\u81f3\u5173\u91cd\u8981\uff08Chang\u7b49\u4eba\uff0c2011\uff09\u3002<\/li><li>\u6324\u538b\u5f0f\u751f\u7269\u6253\u5370\uff1a\u901a\u8fc7\u5c06\u751f\u7269\u58a8\u6c34\u4ece\u55b7\u5634\u6324\u51fa\uff0c\u9002\u7528\u4e8e\u5404\u79cd\u751f\u7269\u6750\u6599\u7c98\u5ea6\uff0c\u64c5\u957f\u5236\u9020\u8f83\u5927\u7684\u7ec4\u7ec7\u7ed3\u6784\uff08Jia\u7b49\u4eba\uff0c2016\uff09\u3002<\/li><li>\u6fc0\u5149\u8f85\u52a9\u751f\u7269\u6253\u5370\uff1a\u8fd9\u79cd\u6280\u672f\u975e\u5e38\u9002\u5408\u5236\u4f5c\u590d\u6742\u7ed3\u6784\uff0c\u5b83\u5229\u7528\u6fc0\u5149\u80fd\u91cf\u7cbe\u786e\u5b9a\u4f4d\u7ec6\u80de\u548c\u6750\u6599\uff0c\u975e\u5e38\u9002\u5408\u9700\u8981\u9ad8\u5206\u8fa8\u7387\u7ec6\u8282\u7684\u7ec4\u7ec7\uff08Keriquel\u7b49\u4eba\uff0c2017\uff09\u3002<\/li><\/ol><p>\u8fd9\u4e9b\u6280\u672f\u53ea\u662f\u51b0\u5c71\u4e00\u89d2\u3002\u5f53\u4e0e\u7ec6\u80de\u5916\u57fa\u8d28\u7684\u5929\u7136\u5149\u6cfd\u76f8\u7ed3\u5408\u65f6\uff0c\u751f\u7269\u6253\u5370\u7684\u6f5c\u529b\u5c06\u5448\u6307\u6570\u7ea7\u589e\u957f\u3002<\/p><p><strong>\u7ec6\u80de\u5916\u57fa\u8d28\uff1a\u81ea\u7136\u754c\u751f\u547d\u7684\u84dd\u56fe<\/strong><\/p><ul><li>\u7ec6\u80de\u5916\u57fa\u8d28\uff08ECM\uff09\u662f\u5927\u81ea\u7136\u7684\u652f\u67b6\u2014\u2014\u7ec4\u7ec7\u548c\u5668\u5b98\u4e2d\u7684\u975e\u7ec6\u80de\u6210\u5206\u3002\u5b83\u63d0\u4f9b\u7269\u7406\u7ed3\u6784\u548c\u751f\u5316\u7ebf\u7d22\uff0c\u6307\u5bfc\u7ec6\u80de\u884c\u4e3a\uff0c\u786e\u4fdd\u7ec4\u7ec7\u968f\u7740\u65f6\u95f4\u7684\u63a8\u79fb\u800c\u53d1\u5c55\u3001\u8fd0\u4f5c\u5e76\u4fdd\u6301\u5b8c\u6574\u6027\u3002ECM\u662f\u7531\u86cb\u767d\u8d28\u3001\u7cd6\u86cb\u767d\u548c\u5176\u4ed6\u5206\u5b50\u7ec4\u6210\u7684\u590d\u6742\u7f51\u7edc\uff0c\u5728\u7ec4\u7ec7\u5065\u5eb7\u4e2d\u53d1\u6325\u7740\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\uff08Frantz\u7b49\u4eba\uff0c2010\uff09\u3002<\/li><li>\u901a\u8fc7\u5229\u7528ECM\u7684\u56fa\u6709\u7279\u6027\uff0c\u79d1\u5b66\u5bb6\u53ef\u4ee5\u5236\u9020\u51fa\u751f\u7269\u58a8\u6c34\uff0c\u652f\u6301\u6253\u5370\u7ec6\u80de\u7684\u5b58\u6d3b\uff0c\u5e76\u5f15\u5bfc\u5176\u751f\u957f\u4e3a\u529f\u80fd\u6027\u7ec4\u7ec7\u3002\u8fd9\u662f\u751f\u7269\u6253\u5370\u548cECM\u4e4b\u95f4\u771f\u6b63\u534f\u540c\u4f5c\u7528\u7684\u4f53\u73b0\u3002<\/li><\/ul><p><strong><br \/>\u534f\u540c\u6548\u5e94\uff1aECM\u5982\u4f55\u5c06\u751f\u7269\u6253\u5370\u6280\u672f\u63d0\u5347\u5230\u65b0\u7684\u9ad8\u5ea6<\/strong><\/p><ul><li>ECM\u4e0e\u751f\u7269\u6253\u5370\u6280\u672f\u7684\u7ed3\u5408\u5e26\u6765\u4e86\u53d8\u9769\u3002ECM\u5982\u4f55\u63d0\u5347\u751f\u7269\u6253\u5370\u6280\u672f\uff0c\u5f15\u9886\u518d\u751f\u533b\u5b66\u7684\u53d1\u5c55\uff1a<\/li><\/ul><p><strong><br \/>\u5353\u8d8a\u7684\u751f\u7269\u58a8\u6c34\u914d\u65b9\uff1a<\/strong><\/p><ul><li>\u57fa\u4e8eECM\u7684\u751f\u7269\u58a8\u6c34\u53ef\u590d\u5236\u7ec4\u7ec7\u7684\u5929\u7136\u5fae\u73af\u5883\uff0c\u4fc3\u8fdb\u7ec6\u80de\u7c98\u9644\u3001\u589e\u6b96\u548c\u5206\u5316\u3002\u8fd9\u786e\u4fdd\u4e86\u6253\u5370\u7684\u7ec4\u7ec7\u66f4\u63a5\u8fd1\u5176\u5929\u7136\u5bf9\u5e94\u7269\uff08Pati\u7b49\u4eba\uff0c2014\uff09\u3002<\/li><li>\u5728\u751f\u7269\u58a8\u6c34\u4e2d\u4f7f\u7528ECM\u53ef\u6784\u5efa\u51fa\u6a21\u62df\u4eba\u4f53\u7ec4\u7ec7\u751f\u7406\u6761\u4ef6\u7684\u7ed3\u6784\uff0c\u4f7f\u5176\u66f4\u9002\u5408\u4e34\u5e8a\u5e94\u7528\u3002<\/li><\/ul><p><strong><br \/>\u63d0\u9ad8\u7ed3\u6784\u5b8c\u6574\u6027\uff1a<\/strong><\/p><ul><li>\u80f6\u539f\u86cb\u767d\u7b49\u86cb\u767d\u8d28\u5b58\u5728\u4e8eECM\u4e2d\uff0c\u56e0\u5176\u4ea4\u8054\u80fd\u529b\u800c\u95fb\u540d\uff0c<br \/>\u53ef\u63d0\u9ad8\u751f\u7269\u6253\u5370\u7ed3\u6784\u7684\u673a\u68b0\u7a33\u5b9a\u6027\uff08Hynes &amp; Naba\uff0c2012\uff09\u3002<\/li><li>\u6df7\u5408\u751f\u7269\u58a8\u6c34\u5c06ECM\u4e0e\u5408\u6210\u805a\u5408\u7269\u76f8\u7ed3\u5408\uff0c\u517c\u5177<br \/>\u5408\u6210\u6750\u6599\u7684\u5f3a\u5ea6\u548c\u5929\u7136\u6750\u6599\u7684\u751f\u7269\u5b66\u76f8\u5173\u6027\uff08Datta et al.\uff0c2017\uff09\u3002<\/li><\/ul><p><strong><br \/>\u7ec4\u7ec7\u7279\u5f02\u6027\u529f\u80fd\uff1a<\/strong><\/p><ul><li>\u4e0d\u540c\u7684\u7ec4\u7ec7\u5177\u6709\u72ec\u7279\u7684ECM\u6210\u5206\u3002\u901a\u8fc7\u8c03\u6574\u751f\u7269\u58a8\u6c34\u4e2d\u7684ECM\u6210\u5206\uff0c\u79d1\u5b66\u5bb6\u53ef\u4ee5\u521b\u5efa\u652f\u6301\u8840\u7ba1\u751f\u6210\uff08\u8840\u7ba1\u7684\u5f62\u6210\uff09\u6216\u795e\u7ecf\u53d1\u751f\uff08\u795e\u7ecf\u7ec4\u7ec7\u7684\u53d1\u80b2\uff09\u7684\u4e13\u7528\u7ec4\u7ec7\uff08Pietraszek\u7b49\u4eba\uff0c2018\uff09\u3002<\/li><\/ul><p><strong><br \/>\u589e\u5f3a\u7ec6\u80de\u6d3b\u529b\u548c\u529f\u80fd\uff1a<\/strong><\/p><ul><li>\u7ec6\u80de\u5916\u57fa\u8d28\u4e0e\u7ec6\u80de\u76f8\u4e92\u4f5c\u7528\uff0c\u4fc3\u8fdb\u7ec4\u7ec7\u5065\u5eb7\u548c\u529f\u80fd\u7684\u91cd\u8981\u4fe1\u53f7\u4f20\u5bfc\u8fc7\u7a0b\uff08Gaharwar\u7b49\u4eba\uff0c2020\uff09\u3002<\/li><li>\u7ec6\u80de\u5916\u57fa\u8d28\u53ef\u4ee5\u9694\u79bb\u548c\u91ca\u653e\u751f\u957f\u56e0\u5b50\uff0c\u786e\u4fdd\u7ec6\u80de\u5728\u9002\u5f53\u7684\u65f6\u95f4\u751f\u957f\u548c\u5206\u5316\u3002<\/li><\/ul><p><strong><br \/><\/strong><strong>\u4f18\u5316\u53ef\u5370\u5237\u6027\uff1a<\/strong><\/p><ul><li>\u57fa\u4e8eECM\u7684\u751f\u7269\u58a8\u6c34\u901a\u5e38\u5177\u6709\u5353\u8d8a\u7684\u6d41\u53d8\u7279\u6027\uff0c\u8fd9\u610f\u5473\u7740\u5b83\u4eec\u5728\u5370\u5237\u8fc7\u7a0b\u4e2d\u66f4\u6613\u6d41\u52a8\uff0c\u4e14\u5728\u5370\u5237\u540e\u80fd\u66f4\u597d\u5730\u4fdd\u6301\u5176\u5f62\u72b6\uff08Groll\u7b49\u4eba\uff0c2016\uff09\u3002<\/li><li>\u8fd9\u4e9b\u751f\u7269\u58a8\u6c34\u53ef\u4ee5\u53d1\u751f\u4e0e\u6e29\u5ea6\u76f8\u5173\u7684\u51dd\u80f6\u5316\uff0c\u4ece\u800c\u4e3a\u5370\u5237\u7ed3\u6784\u63d0\u4f9b\u7a33\u5b9a\u6027\uff0c\u800c\u65e0\u9700\u4f7f\u7528\u6709\u5bb3\u7684\u4ea4\u8054\u5242\u3002<\/li><\/ul><p><strong><br 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\/>\u518d\u751f\u533b\u5b66\uff1a<\/p><ul><li><span style=\"color: var( --e-global-color-text ); letter-spacing: 0.3px; background-color: var( --e-global-color-4f5c74f );\">\u4ece\u70e7\u4f24\u60a3\u8005\u7684\u76ae\u80a4\u79fb\u690d\u5230\u5173\u8282\u4fee\u590d\u7684\u8f6f\u9aa8\uff0c\u751f\u7269\u6253\u5370\u4e0eECM\u7684\u7ed3\u5408\u6b63\u5728\u63a8\u8fdb\u529f\u80fd\u6027\u7ec4\u7ec7\u79fb\u690d\u7684\u73b0\u5b9e\uff08Campbell &amp; Weiss\uff0c2020\uff09\u3002<\/span><\/li><li>\u672a\u6765\uff0c\u53ef\u4ee5\u6839\u636e\u60a3\u8005\u7684\u9700\u6c42\u5b9a\u5236\u6253\u5370\u6574\u4e2a\u5668\u5b98\uff0c\u4ece\u800c\u964d\u4f4e\u6392\u5f02\u53cd\u5e94\u7684\u98ce\u9669\uff0c\u5e76\u6d88\u9664\u6f2b\u957f\u7684\u79fb\u690d\u7b49\u5f85\u65f6\u95f4\u3002<\/li><\/ul><p><strong><br \/>\u836f\u7269\u7814\u53d1\uff1a<\/strong><\/p><ul><li>\u751f\u7269\u6253\u5370\u7684ECM\u7ec4\u7ec7\u4e3a\u6d4b\u8bd5\u63d0\u4f9b\u4e86\u66f4\u903c\u771f\u7684\u6a21\u578b\uff0c\u6709\u671b\u51cf\u5c11\u52a8\u7269\u8bd5\u9a8c\u5e76\u52a0\u901f\u836f\u7269\u7814\u53d1\u8fc7\u7a0b\uff08Knowlton\u7b49\u4eba\uff0c2015\uff09\u3002<\/li><\/ul><p><strong>\u4e2a\u6027\u5316\u533b\u7597\uff1a<\/strong><\/p><ul><li>\u901a\u8fc7\u5c06\u60a3\u8005\u81ea\u8eab\u7684\u7ec6\u80de\u4e0eECM\u589e\u5f3a\u578b\u751f\u7269\u58a8\u6c34\u7ed3\u5408\u4f7f\u7528\uff0c\u79d1\u5b66\u5bb6\u53ef\u4ee5\u521b\u5efa\u4e0e\u4e2a\u4f53\u751f\u7269\u5b66\u76f8\u5339\u914d\u7684\u4e2a\u6027\u5316\u7ec4\u7ec7\u7ed3\u6784\uff0c\u4ece\u800c\u964d\u4f4e\u514d\u75ab\u6392\u65a5\u7684\u98ce\u9669\u5e76\u6539\u5584\u6cbb\u7597\u6548\u679c\uff08Ozbolat\uff0c2017\uff09\u3002<\/li><\/ul><p><strong>\u764c\u75c7\u7814\u7a76\uff1a<\/strong><\/p><ul><li>\u7ed3\u5408ECM\u7684\u751f\u7269\u6253\u5370\u80bf\u7624\u6a21\u578b\u4e3a\u7814\u7a76\u764c\u75c7\u8fdb\u5c55\u548c\u6d4b\u8bd5\u65b0\u7597\u6cd5\u63d0\u4f9b\u4e86\u7cbe\u786e\u7684\u5e73\u53f0\uff0c\u66f4\u771f\u5b9e\u5730\u6a21\u62df\u4e86\u80bf\u7624\u5fae\u73af\u5883\uff08Kang\u7b49\u4eba\uff0c2020\uff09\u3002<\/li><\/ul><p><strong>\u82af\u7247\u5668\u5b98\uff1a<\/strong><\/p><ul><li>\u5c06\u5fae\u6d41\u4f53\u6280\u672f\u4e0e\u589e\u5f3a\u578b\u7ec6\u80de\u5916\u57fa\u8d28\u751f\u7269\u6253\u5370\u6280\u672f\u76f8\u7ed3\u5408\uff0c\u53ef\u4ee5\u5236\u9020\u51fa\u590d\u6742\u7684\u82af\u7247\u5668\u5b98\u6a21\u578b\uff0c\u8fd9\u4e9b\u6a21\u578b\u53ef\u4ee5\u590d\u5236\u4eba\u4f53\u5668\u5b98\u7684\u529f\u80fd\u3002\u8fd9\u4e9b\u6a21\u578b\u53ef\u7528\u4e8e\u75be\u75c5\u5efa\u6a21\u3001\u836f\u7269\u7b5b\u9009\u4ee5\u53ca\u7814\u7a76\u6bd2\u7d20\u548c\u75c5\u539f\u4f53\u7684\u5f71\u54cd\uff08Bhatia\u548cIngber\uff0c2014\uff09\u3002<\/li><\/ul><p><strong>\u6311\u6218\u548c\u672a\u6765\u65b9\u5411\uff1a<\/strong><\/p><p>\u5c3d\u7ba1\u53d6\u5f97\u4e86\u8fdb\u5c55\uff0c\u4f46\u6311\u6218\u4f9d\u7136\u5b58\u5728\uff1a<\/p><ul><li>\u6807\u51c6\u5316\uff1a\u9700\u8981\u57fa\u4e8eECM\u7684\u6807\u51c6\u5316\u751f\u7269\u58a8\u6c34\uff0c\u4ee5\u786e\u4fdd\u5b9e\u9a8c\u5ba4\u4e4b\u95f4\u7684\u53ef\u91cd\u590d\u6027\u548c\u53ef\u9760\u6027\uff08Gopinathan\u548cNoh\uff0c2018\uff09\u3002<\/li><li>\u6269\u5927\u89c4\u6a21\uff1a\u867d\u7136\u5c0f\u89c4\u6a21\u751f\u7269\u6253\u5370\u5df2\u7ecf\u663e\u793a\u51fa\u524d\u666f\uff0c\u4f46\u521b\u5efa\u9002\u5408\u4e34\u5e8a\u4f7f\u7528\u7684\u8f83\u5927\u7ec4\u7ec7\u6216\u5668\u5b98\u4ecd\u7136\u662f\u4e00\u4e2a\u91cd\u5927\u969c\u788d\uff08Moroni\u7b49\u4eba\uff0c2018\uff09\u3002<\/li><li>\u76d1\u7ba1\u969c\u788d\uff1a\u751f\u7269\u6253\u5370\u7ec4\u7ec7\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u5fc5\u987b\u5728\u4e34\u5e8a\u5e94\u7528\u524d\u8fdb\u884c\u4e25\u683c\u7684\u6d4b\u8bd5\u548c\u9a8c\u8bc1\uff08De Coppi\u7b49\u4eba\uff0c2021\uff09\u3002<\/li><\/ul><p><strong>\u6458\u8981\uff1a\u533b\u7597\u65b0\u65f6\u4ee3\u7684\u66d9\u5149<\/strong><\/p><p>\u751f\u7269\u6253\u5370\u4e0e\u7ec6\u80de\u5916\u57fa\u8d28\u7684\u534f\u540c\u4f5c\u7528\u6b63\u5728\u9769\u65b0\u518d\u751f\u533b\u5b66\u3002\u901a\u8fc7\u5c063D\u751f\u7269\u6253\u5370\u7684\u7cbe\u786e\u6027\u4e0e\u7ec6\u80de\u5916\u57fa\u8d28\u7684\u751f\u7269\u5b66\u76f8\u5173\u6027\u76f8\u7ed3\u5408\uff0c\u6211\u4eec\u79bb\u521b\u5efa\u529f\u80fd\u9f50\u5168\u7684\u590d\u6742\u7ec4\u7ec7\u548c\u5668\u5b98\u7684\u76ee\u6807\u66f4\u8fd1\u4e86\u4e00\u6b65\u3002\u968f\u7740\u8be5\u9886\u57df\u7684\u53d1\u5c55\uff0c\u4e2a\u6027\u5316\u3001 \u533b\u7597\u7684\u672a\u6765\u6b63\u5728\u88ab\u4e00\u5c42\u5c42\u6253\u5370\u51fa\u6765\uff0c\u751f\u547d\u672c\u8eab\u7684\u672c\u8d28\u2014\u2014\u7ec6\u80de\u5916\u57fa\u8d28\u2014\u2014\u88ab\u6ce8\u5165\u5230\u6bcf\u4e00\u4e2a\u7ec6\u80de\u548c\u7ed3\u6784\u4e2d\u3002<\/p><p><strong>\u53c2\u8003\u8d44\u6599\uff1a<\/strong><\/p><ul><li>Bhatia, S. N., &amp; Ingber, D. E. (2014). Microfluidic organs-on-chips. <em>Nature Biotechnology<\/em>, 32(8), 760-772.<\/li><li>Campbell, P. G., &amp; Weiss, L. E. (2020). Tissue engineering: The unprecedented advances of bioprinting. <em>Science Translational Medicine<\/em>, 12(536), eaay7962.<\/li><li>Chung, J. W., et al. (2020). Bioprinting strategies for fabricating heterogeneous tissues. <em>Trends in Biotechnology<\/em>, 38(12), 1284-1296.<\/li><li>Datta, P., et al. (2017). Bioink properties for 3D bioprinting. <em>Biotechnology Journal<\/em>, 12(6), 1700150.<\/li><li>De Coppi, P., et al. (2021). Bioprinting tissues and organs. <em>Nature Reviews Bioengineering<\/em>, 2, 123-136.<\/li><li>Frantz, C., et al. (2010). The extracellular matrix at a glance. <em>Journal of Cell Science<\/em>, 123(24), 4195-4200.Gaharwar, A. K., et al. (2020). Mechanically stiff nanocomposite hydrogels for 3D bioprinting. <em>Nature Reviews Materials<\/em>, 5(8), 562-575.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4077af7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4077af7\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-075d01e\" data-id=\"075d01e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u751f\u7269\u6253\u5370\uff1a\u521b\u9020\u751f\u547d\u7684\u827a\u672f\u4e0e\u79d1\u5b66 \u751f\u547d\u79d1\u5b66\u9ad8\u7ea7\u79d1\u5b66\u5bb6Djeda Belharazem\u535a\u58eb djeda.belha <a class=\"read-more\" href=\"https:\/\/biomex.de\/zh-hans\/%e7%94%9f%e7%89%a9%e6%89%93%e5%8d%b0%ef%bc%9a%e5%88%9b%e9%80%a0%e7%94%9f%e5%91%bd%e7%9a%84%e8%89%ba%e6%9c%af%e4%b8%8e%e7%a7%91%e5%ad%a6\/\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-17877","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - 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