{"id":16307,"date":"2022-11-17T14:20:01","date_gmt":"2022-11-17T13:20:01","guid":{"rendered":"https:\/\/biomex-stage.ultrabold.de\/?page_id=16307"},"modified":"2024-10-04T17:45:48","modified_gmt":"2024-10-04T15:45:48","slug":"cellular-starting-materials","status":"publish","type":"page","link":"https:\/\/biomex.de\/zh-hans\/life-sciences\/applications\/cell-and-gene-therapy\/cellular-starting-materials\/","title":{"rendered":"\u7ec6\u80de\u8d77\u59cb\u6750\u6599"},"content":{"rendered":"\t\t
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\u65b0\u9c9c\u7684<\/strong> \u767d\u7ec6\u80de<\/strong> \u5728\u704c\u88c5\u65f6\u81f3\u5c11\u8981\u8fbe\u5230<\/strong> 100 <\/strong>\u4ebf<\/strong>\uff08<\/strong>\u6574\u888b<\/strong> Leukopak<\/strong>\uff09<\/strong>\u6216<\/strong> 50 <\/strong>\u4ebf<\/strong>\uff08<\/strong>\u534a\u888b<\/strong> Leukopak<\/strong>\uff09<\/strong>\u3002\u7136\u800c\uff0c\u6211\u4eec\u9009\u62e9\u4f18\u5148\u8003\u8651\u4ea4\u8d27\u901f\u5ea6\u548c\u4ea7\u54c1\u8d28\u91cf\uff0c\u800c\u4e0d\u662f\u7edd\u5bf9\u7684\u7ec6\u80de\u6570\uff0c\u5982\u679c\u603b\u7ec6\u80de\u6570\u4e0e\u6807\u660e\u7684\u6700\u4f4e\u7ec6\u80de\u6570\u76f8\u6bd4\u504f\u5dee>5%<\/strong>\uff0c\u4e0b\u4e00\u8ba2\u5355\u7684\u4e00\u888b\u4ea7\u54c1\u5c06\u81ea\u52a8\u6253\u6298<\/strong><\/p>

\u65b0\u9c9c\u7684\u767d\u7ec6\u80de\u888b\u7531 BIOMEX \u5728\u5fb7\u56fd\u81ea\u5df1\u7684\u8840\u6d46\u4e2d\u5fc3\u76f4\u63a5\u5206\u79bb\u548c\u8fd0\u9001\uff0c\u5e76\u53ef\u5728\u5206\u79bb\u540e 24 \u5c0f\u65f6\u5185\u9001\u8fbe\u6574\u4e2a\u4e2d\u6b27\u5730\u533a\u3002\u8840\u6d46\u5206\u79bb\u540e\uff0c\u60a8\u5c06\u6536\u5230\u4e00\u4e2a\u8ddf\u8e2a\u94fe\u63a5\uff0c\u5176\u4e2d\u5305\u542b\u534f\u8bae\u3001\u5206\u6790\u8bc1\u4e66\u548c\u5176\u4ed6\u76f8\u5173\u8be6\u7ec6\u4fe1\u606f\u3002\u5206\u6790\u8bc1\u4e66\u4e0a\u62a5\u544a\u7684\u53c2\u6570\u5305\u62ec\u4eba\u53e3\u7edf\u8ba1\u5b66\u6570\u636e\u548c\u4f9b\u4f53\u4fe1\u606f\u3001HLA \u5206\u578b\u3001\u5168\u8840\u7ec6\u80de\u8ba1\u6570\u548c\u4f9b\u4f53\u6c34\u5e73\u7684\u75c5\u539f\u4f53\u68c0\u6d4b\u3002\u53ef\u6839\u636e\u8981\u6c42\u589e\u52a0\u5176\u4ed6\u68c0\u6d4b\u9879\u76ee\u3002<\/p>

\u5982\u9700\u4e86\u89e3\u4e2a\u522b\u4f9b\u4f53\u89c4\u683c\u7684\u4ea4\u8d27\u65f6\u95f4\u3001\u53ec\u56de\u7279\u5b9a\u4f9b\u4f53\u7684\u53ef\u80fd\u6027\u6216\u5411\u4e2d\u6b27\u4ee5\u5916\u56fd\u5bb6\u4f9b\u8d27\u7684\u60c5\u51b5\uff0c\u8bf7\u8054\u7cfb\u6211\u4eec\u7684\u9500\u552e\u56e2\u961f\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\u8bf7\u8054\u7cfb\u6211\u4eec\u7684\u9500\u552e\u56e2\u961f\uff01<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\u51b7\u51bb\u767d\u7ec6\u80de\u7247<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\u4f4e\u6e29\u4fdd\u5b58\u7684\u767d\u7ec6\u80de\u7247\u662f\u6839\u636e IRB \u6279\u51c6\u7684\u65b9\u6848\uff0c\u4ece\u5065\u5eb7\u4e14\u540c\u610f\u7684\u6350\u732e\u8005\u8840\u6db2\uff08\u767d\u7ec6\u80de\u62bd\u5438\u672f\uff09\u5f00\u59cb\uff0c\u7ecf\u8fc7\u7ec6\u80de\u6d53\u7f29\u8fc7\u7a0b\uff0c\u7136\u540e\u518d\u7ecf\u8fc7\u63a7\u5236\u901f\u7387\u7684\u4f4e\u6e29\u4fdd\u5b58\u6b65\u9aa4\u800c\u5f97\u5230\u7684\u3002\u51b7\u51bb\u4fdd\u5b58\u7684\u767d\u7ec6\u80de\u7247\u53ef\u7528\u4f5c\u5206\u79bb\u7279\u5b9a\u514d\u75ab\u7ec6\u80de\u7c7b\u578b\u7684\u8d77\u59cb\u6750\u6599\uff0c\u4ee5\u4fbf\u5728\u53d1\u73b0\u9636\u6bb5\u8fdb\u4e00\u6b65\u51b7\u51bb\u4fdd\u5b58\u548c\u4f7f\u7528\uff0c\u6216\u7528\u4f5c\u5de5\u827a\u5f00\u53d1\u7684\u8d77\u59cb\u6750\u6599\u3002\u5728\u8fd9\u65b9\u9762\uff0c\u4f4e\u6e29\u4fdd\u5b58\u7684\u767d\u7ec6\u80de\u7247\u5c24\u5176\u9002\u7528\u4e8e\u5de5\u827a\u5f00\u53d1\uff0c\u56e0\u4e3a\u5b83\u80fd\u4f7f\u5b9e\u9a8c\u8ba1\u5212\u4e0e\u539f\u6750\u6599\u7684\u7269\u6d41\u8131\u94a9\uff0c\u8ba9\u60a8\u968f\u65f6\u53ef\u4ee5\u5f00\u59cb\u5b9e\u9a8c\uff0c\u5e76\u5728\u8fc7\u7a0b\u4e2d\u8282\u7701\u91cd\u8981\u7684\u65f6\u95f4\u548c\u8d44\u6e90\u3002<\/p>

\u767d\u7ec6\u80de\u5206\u79bb\u4e2d\u7684\u767d\u7ec6\u80de\u6d53\u5ea6\u9ad8\u4e8e\u5168\u8840\uff0c\u5355\u6838\u7ec6\u80de (MNC) \u7684\u6d53\u5ea6\u9ad8\u4e8e\u6c34\u5305\u8863\uff08\u5178\u578b\u6d53\u5ea6\u4e3a 20%\u5355\u6838\u7ec6\u80de\u300150% T \u7ec6\u80de\u300110% B \u7ec6\u80de\u300110% \u81ea\u7136\u6740\u4f24\u7ec6\u80de\u30013% \u7c92\u7ec6\u80de\uff09\u3002\u7ec6\u80de\u5b58\u6d3b\u7387\u548c\u4e0d\u540c\u7ec6\u80de\u7fa4\u7684\u7ec6\u80de\u6570\u5728\u65b0\u9c9c\u548c\u4f4e\u6e29\u4fdd\u5b58\u7684\u767d\u7ec6\u80de\u7247\u4e2d\u76f8\u4f3c\uff0c\u5e76\u5728\u5206\u6790\u8bc1\u4e66\u4e0a\u62a5\u544a\u3002<\/p>

\u5206\u6790\u8bc1\u4e66\u4e0a\u62a5\u544a\u7684\u53c2\u6570\u5305\u62ec\u4eba\u53e3\u7edf\u8ba1\u5b66\u6570\u636e\u548c\u4f9b\u4f53\u4fe1\u606f\u3001HLA \u5206\u578b\u3001\u5168\u8840\u7ec6\u80de\u8ba1\u6570\u548c\u4f9b\u4f53\u6c34\u5e73\u7684\u75c5\u539f\u4f53\u68c0\u6d4b\u3002\u65b0\u4ea7\u54c1\u53ef\u6839\u636e\u8981\u6c42\u589e\u52a0\u5176\u4ed6\u68c0\u6d4b\u9879\u76ee\u3002<\/p>

\u5982\u9700\u54a8\u8be2\u4e2a\u522b\u6350\u732e\u8005\u89c4\u683c\u7684\u4ea4\u8d27\u5468\u671f\u3001\u53ec\u56de\u7279\u5b9a\u6350\u732e\u8005\u7684\u53ef\u80fd\u6027\u6216\u5411\u4e2d\u6b27\u4ee5\u5916\u56fd\u5bb6\u4f9b\u8d27\u7684\u60c5\u51b5\uff0c\u8bf7\u4e0e\u6211\u4eec\u8054\u7cfb\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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PBMC\uff08\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de\uff09\u662f\u5916\u5468\u8840\u767d\u7ec6\u80de\u7684\u4e00\u90e8\u5206\uff0c\u5305\u62ec T \u548c B \u6dcb\u5df4\u7ec6\u80de\u3001NK \u7ec6\u80de\u3001\u5355\u6838\u7ec6\u80de\u548c\u6811\u7a81\u72b6\u7ec6\u80de\u3002\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de\u901a\u5e38\u88ab\u7528\u4f5c\u5206\u79bb\u7279\u5b9a\u7ec6\u80de\u4e9a\u7fa4\u7684\u8d77\u59cb\u6750\u6599\uff0c\u4ee5\u7528\u4e8e\u4e0d\u540c\u7684\u68c0\u6d4b\u3002<\/p>

\u767d\u7ec6\u80de\u4ecb\u5bfc\u7ec6\u80de\uff08PBMC\uff09\u662f\u901a\u8fc7\u5bc6\u5ea6\u68af\u5ea6\u5206\u79bb\u4ece\u767d\u7ec6\u80de\u7624\u4e2d\u5236\u5907\u7684\uff0c\u5e76\u5728\u8fdb\u884c\u7ec6\u80de\u8ba1\u6570\u540e\u4f4e\u6e29\u4fdd\u5b58\u3002\u4e3a\u4e86\u8003\u8651\u51b7\u51bb\u4fdd\u5b58\u8fc7\u7a0b\u4e2d\u53ef\u80fd\u51fa\u73b0\u7684\u7ec6\u80de\u635f\u5931\uff0c\u5e76\u4fdd\u8bc1\u8fbe\u5230\u89c4\u683c\u4e2d\u89c4\u5b9a\u7684\u6700\u4f4e\u5b58\u6d3b\u7ec6\u80de\u6570\uff0c\u4f1a\u5bf9 PBMC \u8fdb\u884c\u8fc7\u91cf\u586b\u5145\u3002\u51b7\u51bb\u7684 PBMC \u968f\u540e\u89e3\u51bb\uff0c\u4ee5\u8fdb\u884c\u8d28\u91cf\u63a7\u5236\uff0c\u5e76\u786e\u8ba4\u5176\u5b58\u6d3b\u7387\u548c\u7ec6\u80de\u6570\u3002BIOMEX \u4ece\u81ea\u5df1\u7684\u8840\u6d46\u4e2d\u5fc3\u5206\u79bb\u51fa\u7684\u767d\u7ec6\u80de\u4e2d\u5206\u79bb\u51fa PBMC\uff0c\u5e76\u80fd\u4fdd\u8bc1\u5728\u63d0\u53d6\u540e 2 \u5c0f\u65f6\u5185\u8fdb\u884c\u51b7\u51bb\u4fdd\u5b58\uff0c\u4ece\u800c\u53ef\u5927\u6279\u91cf\u63d0\u4f9b\u9ad8\u8d28\u91cf\u3001\u672a\u53d7\u523a\u6fc0\u7684 PBMC\uff0c\u4f7f\u591a\u4e2a\u5b9e\u9a8c\u5177\u6709\u6700\u4f73\u7684\u4e00\u81f4\u6027\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

\n\t\t\t
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BIOMEX \u7684 PBMCs \u8ba1\u5212<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de-\u9884\u7b97<\/span><\/i><\/div>

\u8be5\u8ba1\u5212\u4e13\u4e3a\u57fa\u7840\u7814\u7a76\u8bbe\u8ba1\uff0c\u9002\u7528\u4e8e\u521d\u6b65\u7814\u7a76\u6216\u4e0d\u9700\u8981\u9ad8\u7ea7\u4f9b\u4f53\u76f8\u5173\u4fe1\u606f\u7684\u68c0\u6d4b\u3002PBMCs \u9884\u7b97\u7ec6\u80de\u5c06\u8fdb\u884c\u8840\u6e05\u5b66\u68c0\u6d4b\u3002\u5982\u4ee5\u4e0b\u8ba1\u5212\u6240\u793a\uff0c\u53ea\u9700\u652f\u4ed8\u5c11\u91cf\u8d39\u7528\uff0c\u5373\u53ef\u63d0\u4f9b\u5176\u4ed6\u53ef\u9009\u4fe1\u606f\u548c\u68c0\u6d4b\u3002<\/p><\/div>\n\t\t\t\t\t<\/div>

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\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de-\u53d1\u73b0<\/span><\/i><\/div>

\u8be5\u8ba1\u5212\u4e13\u4e3a\u836f\u7269\u53d1\u73b0\u65b9\u6cd5\uff08\u5305\u62ec\u9776\u70b9\u9a8c\u8bc1\u3001\u5148\u5bfc\u7269\u9274\u5b9a\u548c\u4f18\u5316\uff09\u4e2d\u4f7f\u7528\u7684\u68c0\u6d4b\u800c\u8bbe\u8ba1\u3002\u5b83\u63d0\u4f9b\u5b8c\u6574\u7684\u4f9b\u4f53\u4fe1\u606f\uff0c\u5305\u62ec\u4eba\u53e3\u7edf\u8ba1\u5b66\u3001\u8840\u6e05\u5b66\u3001HLA I \u7c7b\u548c II \u7c7b\u7279\u5f81\u3001FCGR3A \u591a\u6001\u6027\u3001\u5438\u70df\u72b6\u51b5\u3001\u89e3\u51bb\u524d\u548c\u89e3\u51bb\u540e\u8840\u6db2\u5b66\u5206\u6790\u3001\u836f\u7269\u3001\u8fc7\u654f\u548c\u5176\u4ed6\u75be\u75c5\u3002\u767d\u7ec6\u80de\u4ecb\u5bfc\u7ec6\u80de\uff08PBMCs\uff09–\u53d1\u73b0\u65f6\u8fdb\u884c\u65e0\u83cc\u548c\u7ec6\u80de\u6d3b\u5316\u6d4b\u8bd5\u3002<\/p><\/div>\n\t\t\t\t\t<\/div>

\n\t\t\t\t\t
\u4e34\u5e8a\u524d\u6837\u672c<\/span><\/i><\/div>

\u8be5\u8ba1\u5212\u7528\u4e8e\u4e34\u5e8a\u524d\u8bd5\u9a8c\u4e2d\u4f7f\u7528\u7684\u68c0\u6d4b\u65b9\u6cd5\uff0c\u5305\u62ec\u514d\u75ab\u539f\u6027\u3001\u514d\u75ab\u6bd2\u6027\u3001\u673a\u7406\u6bd2\u7406\u5b66\u548c\u7814\u7a76\u6bd2\u7406\u5b66\u3002\u63d0\u4f9b\u5b8c\u6574\u7684\u4f9b\u4f53\u4fe1\u606f\uff0c\u5305\u62ec\u4eba\u53e3\u7edf\u8ba1\u5b66\u3001\u8840\u6e05\u5b66\u3001HLA I \u7c7b\u548c II \u7c7b\u7279\u5f81\u3001FCGR3A \u591a\u6001\u6027\u3001\u5438\u70df\u72b6\u51b5\u3001\u89e3\u51bb\u524d\u548c\u89e3\u51bb\u540e\u8840\u6db2\u5b66\u5206\u6790\u3001\u836f\u7269\u3001\u8fc7\u654f\u548c\u5176\u4ed6\u75be\u75c5\u3002\u5bf9\u53d1\u73b0\u7684 PBMC \u8fdb\u884c\u65e0\u83cc\u548c\u7ec6\u80de\u6d3b\u5316\u6d4b\u8bd5\u3002\u6b64\u5916\uff0c\u8fd8\u53ef\u63d0\u4f9b\u6765\u81ea\u540c\u4e00\u60a3\u8005\u7684\u5339\u914d\u8840\u6d46\u6216\u8840\u6e05\uff081 \u6beb\u5347\u4f4e\u6e29\u4fdd\u5b58\u7b49\u5206\u6837\u54c1\uff09\u3002<\/p><\/div>\n\t\t\t\t\t<\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\u8bf7\u8054\u7cfb\u6211\u4eec\u7684\u9500\u552e\u56e2\u961f\uff01<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\u6211\u4eec\u63d0\u4f9b\u7684\u7ec6\u80de\u548c\u57fa\u56e0\u7597\u6cd5\u5b89\u5168\u6d4b\u8bd5<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\u7ec6\u80de\u548c\u57fa\u56e0\u7597\u6cd5\u7684\u5b89\u5168\u6027\u6d4b\u8bd5\u662f\u4e34\u5e8a\u524d\u548c\u4e34\u5e8a\u5f00\u53d1\u8fc7\u7a0b\u4e2d\u6700\u91cd\u8981\u7684\u6b65\u9aa4\u4e4b\u4e00\u3002\u867d\u7136\u5305\u62ec T \u7ec6\u80de\u53d7\u4f53\u5de5\u7a0b T \u7ec6\u80de (TCR-T)\u3001\u5d4c\u5408\u6297\u539f\u53d7\u4f53 T \u7ec6\u80de (CAR-T) \u548c\u80bf\u7624\u6d78\u6da6\u6dcb\u5df4\u7ec6\u80de (TIL) \u5728\u5185\u7684\u9886\u517b\u7ec6\u80de\u7597\u6cd5 (ACT) \u88ab\u8bc1\u660e\u5bf9\u764c\u75c7\u6cbb\u7597\u975e\u5e38\u6709\u6548\uff0c\u4f46\u5b83\u4eec\u4e5f\u4e0e\u8f7b\u5fae\u5230\u5371\u53ca\u751f\u547d\u7684\u9776\u4e0a\u6bd2\u6027\u3001\u8131\u9776\u6bd2\u6027\u548c\u514d\u75ab\u6fc0\u6d3b\u5bfc\u81f4\u7684\u6bd2\u6027\uff08\u5982\u7ec6\u80de\u56e0\u5b50\u91ca\u653e\u7efc\u5408\u5f81 (CRS)\uff09\u6709\u5173\u3002\u540c\u6837\uff0c\u57fa\u56e0\u7597\u6cd5\u4e5f\u88ab\u62a5\u9053\u4e0e\u9776\u4e0a\u548c\u9776\u4e0b\u6bd2\u6027\u6709\u5173\u3002\u6b64\u5916\uff0c\u7279\u522b\u662f\u817a\u76f8\u5173\u75c5\u6bd2\uff08AAV\uff09\uff0c\u4e3a\u514b\u670d\u9488\u5bf9\u5e3d\u4fa7\u86cb\u767d\u7684\u6297\u4f53\u4ea7\u751f\u7684\u57fa\u7ebf\uff0c\u5fc5\u987b\u4f7f\u7528\u9ad8\u5242\u91cf\u7684\u75c5\u6bd2\u8f7d\u4f53\uff0c\u8fd9\u5bfc\u81f4\u4e86\u4e25\u91cd\u7684\u4e0d\u826f\u4e8b\u4ef6\uff0c\u5982\u809d\u6bd2\u6027\u548c\u80cc\u6839\u795e\u7ecf\u8282\u6bd2\u6027\u3002<\/p>

\u6211\u4eec\u63d0\u4f9b\u7684\u7ec6\u80de\u548c\u57fa\u56e0\u7597\u6cd5\u5b89\u5168\u6027\u6d4b\u8bd5\u5305\u62ec\u7528\u4e8e\u514d\u75ab\u539f\u6027\u548c\u514d\u75ab\u6bd2\u6027\u6d4b\u8bd5\u7684 PBMCs \u9762\u677f\uff0c\u53ef\u4f7f\u7528\u6216\u4e0d\u4f7f\u7528\u5339\u914d\u7684\u8840\u6d46\u548c\u8840\u6e05\u3002\u5982\u679c\u60a8\u5e0c\u671b\u8282\u7701\u65f6\u95f4\u548c\u8d44\u6e90\uff0c\u6211\u4eec\u7684\u4e13\u5bb6\u670d\u52a1\u56e2\u961f\u5c06\u4e0e\u60a8\u5408\u4f5c\uff0c\u52a0\u901f\u60a8\u7684\u4ea7\u54c1\u7ebf\u8fdb\u5c55\u3002\u5982\u9700\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8054\u7cfb\u6211\u4eec\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\u8054\u7cfb\u6211\u4eec\u7684\u9500\u552e\u56e2\u961f\uff01<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\u514d\u75ab\u539f\u6027\u548c\u514d\u75ab\u6bd2\u6027\u68c0\u6d4b\u677f<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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BIOMEX \u7684\u514d\u75ab\u539f\u6027\u548c\u514d\u75ab\u6bd2\u6027\u8bd5\u5242\u76d2\u8bbe\u8ba1\u7528\u4e8e\u652f\u6301\u4e34\u5e8a\u524d\u548c\u4e34\u5e8a\u9636\u6bb5\u5927\u5206\u5b50\u3001\u7ec6\u80de\u7597\u6cd5\u548c\u57fa\u56e0\u7597\u6cd5\u7684\u5185\u90e8\u5b89\u5168\u6027\u6d4b\u8bd5\u3002\u8bd5\u5242\u76d2\u7684\u914d\u7f6e\u9002\u5408\u518d\u73b0\u767d\u79cd\u4eba\u4e2d\u6700\u5e38\u89c1\u7684 HLA I \u7c7b\u6216 II \u7c7b\u7b49\u4f4d\u57fa\u56e0\u7684\u5168\u90e8\u8303\u56f4\uff0c\u9002\u7528\u4e8e\u9996\u6b21\u7b5b\u9009\u8bd5\u9a8c\u3002\u5982\u679c\u9700\u8981\uff0c\u6211\u4eec\u8fd8\u53ef\u6839\u636e\u5ba2\u6237\u8981\u6c42\u7ec4\u88c5\u7528\u4e8e\u7279\u5b9a\u7b49\u4f4d\u57fa\u56e0\u68c0\u6d4b\u7684\u8bd5\u5242\u76d2\u3002<\/p>

\u514d\u75ab\u539f\u6027\u548c\u514d\u75ab\u6bd2\u6027\u8bd5\u5242\u76d2\u5404 100 \u74f6\uff0c\u76f8\u5f53\u4e8e 10 \u74f6 \u00e0 20 \u767e\u4e07\u5b58\u6d3b\u7684\u4f4e\u6e29\u4fdd\u5b58 PBMCs\/\u74f6\/\u4f9b\u4f53\uff0c\u4f9b 10 \u4f4d\u4f9b\u4f53\u4f7f\u7528\u3002\u5bf9\u51b7\u51bb\u4fdd\u5b58\u7684 PBMCs \u8fdb\u884c\u65e0\u83cc\u3001\u8840\u6e05\u5b66\u548c\u7ec6\u80de\u6d3b\u5316\u6d4b\u8bd5\uff0c\u5e76\u9884\u5148\u8fdb\u884c T \u7ec6\u80de\u589e\u6b96\u8bd5\u9a8c\u548c DC:T \u7ec6\u80de\u523a\u6fc0\u8bd5\u9a8c\u3002\u6709\u5173\u4eba\u53e3\u7edf\u8ba1\u5b66\u3001\u65e2\u5f80\u4e34\u5e8a\u75c5\u53f2\u548c\u89e3\u51bb\u524d\u540e\u8840\u6db2\u5b66\u5206\u6790\u7684\u6570\u636e\u53ef\u5e94\u8981\u6c42\u63d0\u4f9b\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

\n\t\t\t
\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\u53ef\u63d0\u4f9b\u4ee5\u4e0b\u68c0\u6d4b\u7248\uff1a<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n
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ImmunoSafe\u2122-HLA1<\/span><\/i><\/div>

\u8be5\u68c0\u6d4b\u677f\u5305\u542b 10 \u4e2a\u4e0d\u540c\u7684\u4f9b\u4f53\uff0c\u4ee5\u6db5\u76d6\u767d\u79cd\u4eba\u4e2d\u6700\u5e38\u89c1\u7684 HLA I \u7c7b\u7b49\u4f4d\u57fa\u56e0\uff0c\u901a\u5e38\u4e5f\u5305\u542b\u4e00\u4e9b\u4e0d\u5e38\u89c1\u7684\u7b49\u4f4d\u57fa\u56e0\u3002ImmunoSafe\u2122-HLA1 \u68c0\u6d4b\u677f\u4e3a\u73b0\u8d27\u4f9b\u5e94\uff0c\u53ef\u5728\u6b21\u65e5\u53d1\u8d27\u3002\u5982\u679c\u9762\u677f\u6ca1\u6709\u73b0\u8d27\uff0c\u4ea4\u8d27\u671f\u53ef\u80fd\u957f\u8fbe 3 \u5468\u3002\u5982\u9700\u54a8\u8be2\u7279\u5b9a\u8bd5\u5242\u76d2\u7684\u4ea4\u8d27\u65f6\u95f4\uff0c\u8bf7\u8054\u7cfb\u6211\u4eec\u7684\u9500\u552e\u56e2\u961f\u3002<\/p><\/div>\n\t\t\t\t\t<\/div>

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ImmunoSafe\u2122-HLA2<\/span><\/i><\/div>

\u8be5\u8bd5\u5242\u76d2\u5305\u542b 10 \u4e2a\u4e0d\u540c\u7684\u4f9b\u4f53\uff0c\u4ee5\u6db5\u76d6\u767d\u79cd\u4eba\u4e2d\u6700\u5e38\u89c1\u7684 HLA II \u7c7b\u7b49\u4f4d\u57fa\u56e0\uff0c\u901a\u5e38\u8fd8\u5305\u542b\u4e00\u4e9b\u4e0d\u5e38\u89c1\u7684\u7b49\u4f4d\u57fa\u56e0\u3002ImmunoSafe\u2122-HLA2 \u8840\u5c0f\u677f\u662f\u73b0\u6210\u4ea7\u54c1\uff0c\u53ef\u5728\u6b21\u65e5\u53d1\u8d27\u3002\u5982\u679c\u9762\u677f\u6ca1\u6709\u73b0\u8d27\uff0c\u4ea4\u8d27\u671f\u53ef\u80fd\u957f\u8fbe 3 \u5468\u3002\u5982\u9700\u54a8\u8be2\u7279\u5b9a\u8bd5\u5242\u76d2\u7684\u4ea4\u8d27\u65f6\u95f4\uff0c\u8bf7\u8054\u7cfb\u6211\u4eec\u7684\u9500\u552e\u56e2\u961f\u3002<\/p><\/div>\n\t\t\t\t\t<\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\u5339\u914d\u8840\u6d46\u548c\u8840\u6e05<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\u53ef\u5e94\u8981\u6c42\u63d0\u4f9b\u914d\u5bf9\u8840\u6d46\u548c\u8840\u6e05\uff0c\u8fd9\u4e9b\u8840\u6d46\u548c\u8840\u6e05\u6765\u81ea ImmunoSafe\u2122 \u68c0\u6d4b\u677f\u4e2d\u7684\u4f9b\u4f53\uff0c\u6bcf\u4efd 1 \u6beb\u5347\u3002\u5bf9\u4e8e\u5b9a\u5236\u8bd5\u5242\u76d2\u548c\u65b0\u4ea7\u54c1\uff0c\u524d\u7f6e\u65f6\u95f4\u53ef\u80fd\u957f\u8fbe 3 \u5468\u3002\u5982\u9700\u54a8\u8be2\u7279\u5b9a\u8bd5\u5242\u76d2\u7ec4\u6210\u6216\u4e0d\u540c\u7b49\u5206\u8bd5\u5242\u76d2\u683c\u5f0f\u7684\u4ea4\u8d27\u65f6\u95f4\uff0c\u8bf7\u8054\u7cfb\u6211\u4eec\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t<\/span>\n\t\t\t\t2000000<\/span>\n\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t \u8bbf\u95ee\u6211\u4eec\u7684\u751f\u7269\u6837\u672c\u5546\u5e97<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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